The Culture Collection of Soil Actinomycetes České Budějovice (CCSACB) was founded in the Institute of Soil Biology, Biology Centre CAS, v. v. i. in 2007. The CCSACB became a member of Biology Centre Collection of Organisms (BCCO) in 2015. The CCSACB serves as a depository for cultures of soil actinomycetes, used mainly for screening of strains producing important secondary metabolites. Moreover, the CCSACB isolates can be used for research, industrial applications, education, and general scientific interest. Most of the cultures belong to the family Streptomycetaceae (genera Streptomyces, Streptacidiphilus and Kitasatospora), however some other families are also represented (Pseudonocardiaceae: gg. Kutzneria, Letznea, Amycolatopsis, Saccharothrix, Nocardiaceae: gg. Nocardia and Nonomurea, Nocardioidaceae: g. Kribella, Micromonosporaceae: gg. Actinoplanes, Micromonospora and Pillimelia, Streptosporangiaceae: g. Microbispora).
The major activity of the CCSACB is preserving actinomycetes which were isolated from soil and sediments of some unique habitats (agricultural fields, gardens, native prairies, savannahs, temporal forest, tropical rainforest, grassland, bat guano, caves, glacier forefields, Miocene lacustrine sediment, iron ore mining sediment (technozem), brown coal colliery spoil, dead bees, ambrosia beetle galleries, potato surface, etc.).
We are opened to cooperate with research institutes, universities and pharmaceutical companies on research of substances with antibiotic or anti-inflammatory effect. Moreover, members of genus Streptomyces are recognized as the producers of many bioactive metabolites that are useful:
- in medicine as antifungals, antivirals, antithrombotics, immunomodifiers, antitumor drugs and enzyme inhibitors
- in agriculture as insecticides, herbicides, fungicides and growth promoting substances for plants and animals.
The webpages actualisation and development are funded by the project Strategy AV21 Diversity of Life and Health of Ecosystems.
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